Wouter H Moolenaar Selected Research

alkylglycerophosphoethanolamine phosphodiesterase

1/2013	The polybasic insertion in autotaxin α confers specific binding to heparin and cell surface heparan sulfate proteoglycans.
12/2011	Autotaxin and LPA receptor signaling in cancer.
3/2009	Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis.
8/2008	Anticancer activity of FTY720: phosphorylated FTY720 inhibits autotaxin, a metastasis-enhancing and angiogenic lysophospholipase D.
7/2006	Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development.
7/2002	Lysophospholipids in the limelight: autotaxin takes center stage.

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Wouter H Moolenaar Research Topics

Disease

15	Neoplasms (Cancer) 01/2022 - 07/2002
5	Neuroblastoma 10/2020 - 01/2003
5	Neoplasm Metastasis (Metastasis) 08/2008 - 11/2003
3	Inflammation (Inflammations) 11/2016 - 04/2010
2	Breast Neoplasms (Breast Cancer) 01/2017 - 06/2009
2	Fibrosis (Cirrhosis) 11/2016 - 04/2016
2	Pruritus (Itching) 04/2016 - 09/2010
2	Carcinoma (Carcinomatosis) 01/2007 - 05/2006
1	Colitis 01/2019
1	Colorectal Neoplasms (Colorectal Cancer) 01/2019
1	Melanoma (Melanoma, Malignant) 02/2016
1	Pathologic Processes 01/2013
1	Urinary Bladder Neoplasms (Bladder Cancer) 12/2011
1	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 09/2010
1	Intrahepatic Cholestasis of Pregnancy 09/2010
1	Carcinogenesis 06/2009
1	Thrombosis (Thrombus) 03/2009
1	Hemorrhage 03/2009
1	Disease Susceptibility (Diathesis) 03/2009
1	Vascular Remodeling 09/2008
1	Herpes Zoster 06/2007
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 05/2006
1	Lymphatic Metastasis 11/2003
1	Ovarian Neoplasms (Ovarian Cancer) 06/2002

Drug/Important Bio-Agent (IBA)

10	lysophosphatidic acidIBA 11/2016 - 06/2002
6	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2022 - 08/2004
6	alkylglycerophosphoethanolamine phosphodiesteraseIBA 01/2013 - 07/2002
5	Lysophosphatidic Acid ReceptorsIBA 01/2019 - 01/2003
3	nucleotide pyrophosphataseIBA 01/2022 - 06/2005
3	LipidsIBA 01/2013 - 08/2008
3	Lysophosphatidylcholines (Lysophosphatidylcholine)IBA 12/2011 - 07/2002
3	EnzymesIBA 09/2010 - 08/2003
2	Phospholipids (Phosphatides)FDA LinkGeneric 01/2022 - 05/2014
2	Biological ProductsIBA 01/2022 - 04/2016
2	NucleotidesIBA 01/2022 - 08/2008
2	Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA 10/2020 - 01/2017
2	GlypicansIBA 12/2016 - 10/2016
2	glycerophosphodiester phosphodiesteraseIBA 12/2016 - 10/2016
2	CortactinIBA 05/2006 - 11/2003
1	O-ethyl O-4-nitrophenyl phosphoramidateIBA 01/2022
1	GPI-Linked ProteinsIBA 10/2020
1	Phospholipase DIBA 10/2020
1	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 01/2017
1	Urokinase Plasminogen Activator ReceptorsIBA 01/2017
1	Type C PhospholipasesIBA 01/2017
1	Proteins (Proteins, Gene)FDA Link 01/2017
1	Endothelins (Endothelin)IBA 02/2016
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 02/2016
1	miltefosine (Impavido)IBA 05/2014
1	perifosineIBA 05/2014
1	erucylphosphocholineIBA 05/2014
1	ilmofosineIBA 05/2014
1	edelfosineIBA 05/2014
1	Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)IBA 12/2011
1	Biomarkers (Surrogate Marker)IBA 11/2010
1	CalciumIBA 09/2010
1	Histamine (Histamine Dihydrochloride)FDA Link 09/2010
1	Opioid Analgesics (Opioids)IBA 09/2010
1	Bile Acids and Salts (Bile Acids)IBA 09/2010
1	Tryptases (Tryptase)IBA 09/2010
1	Substance PIBA 09/2010
1	IntegrinsIBA 03/2009
1	PyrophosphatasesIBA 08/2008
1	Fingolimod Hydrochloride (FTY720)FDA Link 08/2008
1	Connexin 43 (Connexin43)IBA 06/2007
1	Transcription Factors (Transcription Factor)IBA 01/2007
1	Tyrosine (L-Tyrosine)FDA Link 11/2003

Therapy/Procedure

2	Therapeutics 04/2010 - 08/2003
1	Radiotherapy 05/2014
1	Immunomodulation 08/2008